One-domain CD4 Fused to Human Anti-CD16 Antibody Domain Mediates Effective Killing of HIV-1-Infected Cells

Bispecific killer cells engagers (BiKEs) which can bind to natural killer (NK) cells through the activating receptor CD16A and guide them to cells expressing the HIV-1 envelope glycoprotein (Env) are a promising new weapon for elimination of infected cells and eradication of the virus. Here we repor...

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Detalles Bibliográficos
Autores principales: Li, Wei, Wu, Yanling, Kong, Desheng, Yang, Hongjia, Wang, Yanping, Shao, Jiping, Feng, Yang, Chen, Weizao, Ma, Liying, Ying, Tianlei, Dimitrov, Dimiter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567353/
https://www.ncbi.nlm.nih.gov/pubmed/28831040
http://dx.doi.org/10.1038/s41598-017-07966-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567353/
https://www.ncbi.nlm.nih.gov/pubmed/28831040
http://dx.doi.org/10.1038/s41598-017-07966-3

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