Stress-Induced Protein S-Glutathionylation and S-Trypanothionylation in African Trypanosomes—A Quantitative Redox Proteome and Thiol Analysis

Aims: Trypanosomatids have a unique trypanothione-based thiol redox metabolism. The parasite-specific dithiol is synthesized from glutathione and spermidine, with glutathionylspermidine as intermediate catalyzed by trypanothione synthetase. In this study, we address the oxidative stress response of...

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Detalles Bibliográficos
Autores principales: Ulrich, Kathrin, Finkenzeller, Caroline, Merker, Sabine, Rojas, Federico, Matthews, Keith, Ruppert, Thomas, Krauth-Siegel, R. Luise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2017
Materias:
Original Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567454/
https://www.ncbi.nlm.nih.gov/pubmed/28338335
http://dx.doi.org/10.1089/ars.2016.6947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567454/
https://www.ncbi.nlm.nih.gov/pubmed/28338335
http://dx.doi.org/10.1089/ars.2016.6947

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