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Ginkgetin aglycone ameliorates LPS-induced acute kidney injury by activating SIRT1 via inhibiting the NF-κB signaling pathway

BACKGROUND: Ginkgetin aglycone (GA), a novel Ginkgo biloba extract (GBE) by acid hydrolysis and recrystallization, is characterized by higher liposolubility and antioxidation than classical GBEs. There is no study depicting the functional role of GA in acute kidney injury (AKI). Here, we firstly rep...

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Detalles Bibliográficos
Autores principales: Zhang, Junwei, Yang, Suxia, Chen, Fang, Li, Huicong, Chen, Baoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567569/
https://www.ncbi.nlm.nih.gov/pubmed/28852469
http://dx.doi.org/10.1186/s13578-017-0173-3