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MicroRNA-218 functions as a tumor suppressor in lung cancer by targeting IL-6/STAT3 and negatively correlates with poor prognosis

BACKGROUND: Aberrant expression of microRNAs in different human cancer types has been widely reported. MiR-218 acts as a tumor suppressor in diverse human cancer types impacting regulation of multiple genes in oncogenic pathways. Here, we evaluated the expression and function of miR-218 in human lun...

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Detalles Bibliográficos
Autores principales: Yang, Yan, Ding, Lili, Hu, Qun, Xia, Jia, Sun, Junjie, Wang, Xudong, Xiong, Hua, Gurbani, Deepak, Li, Lianbo, Liu, Yan, Liu, Aiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567631/
https://www.ncbi.nlm.nih.gov/pubmed/28830450
http://dx.doi.org/10.1186/s12943-017-0710-z