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Integration of the tricarboxylic acid (TCA) cycle with cAMP signaling and Sfl2 pathways in the regulation of CO(2) sensing and hyphal development in Candida albicans

Morphological transitions and metabolic regulation are critical for the human fungal pathogen Candida albicans to adapt to the changing host environment. In this study, we generated a library of central metabolic pathway mutants in the tricarboxylic acid (TCA) cycle, and investigated the functional...

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Detalles Bibliográficos
Autores principales: Tao, Li, Zhang, Yulong, Fan, Shuru, Nobile, Clarissa J., Guan, Guobo, Huang, Guanghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567665/
https://www.ncbi.nlm.nih.gov/pubmed/28787458
http://dx.doi.org/10.1371/journal.pgen.1006949