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Role of MEK partner-1 in cancer stemness through MEK/ERK pathway in cancerous neural stem cells, expressing EGFRviii

BACKGROUND: Glioma stem cells (GSCs) are a major cause of the frequent relapse observed in glioma, due to their high drug resistance and their differentiation potential. Therefore, understanding the molecular mechanisms governing the ‘cancer stemness’ of GSCs will be particularly important for impro...

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Detalles Bibliográficos
Autores principales: Kwon, Soo-Jung, Kwon, Ok-Seon, Kim, Keun-Tae, Go, Young-Hyun, Yu, Si-in, Lee, Byeong-ha, Miyoshi, Hiroyuki, Oh, Eunsel, Cho, Seung-Ju, Cha, Hyuk-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567886/
https://www.ncbi.nlm.nih.gov/pubmed/28830458
http://dx.doi.org/10.1186/s12943-017-0703-y