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Visualizing multistep elevator-like transitions of a nucleoside transporter
Membrane transporters move substrates across the membrane by alternating access of their binding sites to one side of the membrane at a time. An emerging model is the elevator mechanism in which a substrate-binding transport domain moves a large distance across the membrane. This mechanism has been...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567992/ https://www.ncbi.nlm.nih.gov/pubmed/28424521 http://dx.doi.org/10.1038/nature22057 |