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The use of primary murine fibroblasts to ascertain if Spirocerca lupi secretory/excretory protein products are mitogenic ex vivo

BACKGROUND: Spirocerca lupi is a nematode that parasitizes vertebrates in particular canids, by forming nodules in the thoracic cavity specifically in the oesophagus. In 25% of Spirocerca infections of the domestic dog, nodules progress from inflammatory to pre-neoplastic to sarcomatous neoplasia. W...

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Detalles Bibliográficos
Autores principales: Sako, Kgomotso, Rensburg, Ilse jv, Clift, Sarah, Naidoo, Vinny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568052/
https://www.ncbi.nlm.nih.gov/pubmed/28830546
http://dx.doi.org/10.1186/s12917-017-1162-9