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Variants of sequence family B Thermococcus kodakaraensis DNA polymerase with increased mismatch extension selectivity

Fidelity and selectivity of DNA polymerases are critical determinants for the biology of life, as well as important tools for biotechnological applications. DNA polymerases catalyze the formation of DNA strands by adding deoxynucleotides to a primer, which is complementarily bound to a template. To...

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Detalles Bibliográficos
Autores principales: Huber, Claudia, Marx, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568139/
https://www.ncbi.nlm.nih.gov/pubmed/28832623
http://dx.doi.org/10.1371/journal.pone.0183623