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Metabolic profiling of triple-negative breast cancer cells reveals metabolic vulnerabilities

BACKGROUND: Among breast cancers, the triple-negative breast cancer (TNBC) subtype has the worst prognosis with no approved targeted therapies and only standard chemotherapy as the backbone of systemic therapy. Unique metabolic changes in cancer progression provide innovative therapeutic opportuniti...

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Detalles Bibliográficos
Autores principales: Lanning, Nathan J., Castle, Joshua P., Singh, Simar J., Leon, Andre N., Tovar, Elizabeth A., Sanghera, Amandeep, MacKeigan, Jeffrey P., Filipp, Fabian V., Graveel, Carrie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568171/
https://www.ncbi.nlm.nih.gov/pubmed/28852500
http://dx.doi.org/10.1186/s40170-017-0168-x