In vitro aggregating β-lactamase-polyQ chimeras do not induce toxic effects in an in vivo Caenorhabditis elegans model

BACKGROUND: A series of human diseases are caused by the misfolding and aggregation of specific proteins or peptides into amyloid fibrils; nine of these diseases, referred to as polyglutamine diseases, are associated with proteins carrying an expanded polyglutamine (polyQ) region. While the presence...

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Detalles Bibliográficos
Autores principales: Van Assche, Roel, Borghgraef, Charline, Vaneyck, Jonathan, Dumoulin, Mireille, Schoofs, Liliane, Temmerman, Liesbet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568214/
https://www.ncbi.nlm.nih.gov/pubmed/28830560
http://dx.doi.org/10.1186/s12952-017-0080-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568214/
https://www.ncbi.nlm.nih.gov/pubmed/28830560
http://dx.doi.org/10.1186/s12952-017-0080-5

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