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Rates of switching to second-line antiretroviral therapy and impact of delayed switching on immunologic, virologic, and mortality outcomes among HIV-infected adults with virologic failure in Rakai, Uganda

BACKGROUND: Switch from first to second-line ART is recommended by WHO for patients with virologic failure. Delays in switching may contribute to accumulated drug resistance, advanced immunosuppression, increased morbidity and mortality. The 3rd 90′ of UNAIDS 90:90:90 targets 90% viral suppression f...

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Detalles Bibliográficos
Autores principales: Ssempijja, Victor, Nakigozi, Gertrude, Chang, Larry, Gray, Ron, Wawer, Maria, Ndyanabo, Anthony, Kasule, Jingo, Serwadda, David, Castelnuovo, Barbara, Hoog, Anja van’t, Reynolds, Steven James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568262/
https://www.ncbi.nlm.nih.gov/pubmed/28830382
http://dx.doi.org/10.1186/s12879-017-2680-6