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Effect of naringin on gp120-induced injury mediated by P2X(7) receptors in rat primary cultured microglia

Human immunodeficiency virus type-1 (HIV-1) envelope glycoprotein 120 has been shown to activate microglia, causing release of inflammatory and toxic factors. The P2X(7) receptor, primarily expressed on microglia, is closely associated with inflammation. Naringin, a plant bioflavonoid, has anti-infl...

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Detalles Bibliográficos
Autores principales: Chen, Qiang, Wu, Hui, Tao, Jia, Liu, Chenglong, Deng, Zeyu, Liu, Yang, Chen, Guoqiao, Liu, Baoyun, Xu, Changshui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568276/
https://www.ncbi.nlm.nih.gov/pubmed/28832643
http://dx.doi.org/10.1371/journal.pone.0183688