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Effect of naringin on gp120-induced injury mediated by P2X(7) receptors in rat primary cultured microglia
Human immunodeficiency virus type-1 (HIV-1) envelope glycoprotein 120 has been shown to activate microglia, causing release of inflammatory and toxic factors. The P2X(7) receptor, primarily expressed on microglia, is closely associated with inflammation. Naringin, a plant bioflavonoid, has anti-infl...
Autores principales: | Chen, Qiang, Wu, Hui, Tao, Jia, Liu, Chenglong, Deng, Zeyu, Liu, Yang, Chen, Guoqiao, Liu, Baoyun, Xu, Changshui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568276/ https://www.ncbi.nlm.nih.gov/pubmed/28832643 http://dx.doi.org/10.1371/journal.pone.0183688 |
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