Development of a fluorescent reporter system for monitoring ER stress in Chinese hamster ovary cells and its application for therapeutic protein production

Mammalian cell expression systems have become a workhorse for the production of biotherapeutic proteins. As such, there is an ever increasing demand for higher productivity from these expression platforms to reduce manufacturing costs. While great advances have been made in the optimization of cultu...

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Detalles Bibliográficos
Autores principales: Roy, Gargi, Zhang, Shu, Li, Lina, Higham, Eileen, Wu, Herren, Marelli, Marcello, Bowen, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568292/
https://www.ncbi.nlm.nih.gov/pubmed/28832690
http://dx.doi.org/10.1371/journal.pone.0183694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568292/
https://www.ncbi.nlm.nih.gov/pubmed/28832690
http://dx.doi.org/10.1371/journal.pone.0183694

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