HPN-07, a free radical spin trapping agent, protects against functional, cellular and electrophysiological changes in the cochlea induced by acute acoustic trauma

Oxidative stress is considered a major cause of the structural and functional changes associated with auditory pathologies induced by exposure to acute acoustic trauma AAT). In the present study, we examined the otoprotective effects of 2,4-disulfophenyl-N-tert-butylnitrone (HPN-07), a nitrone-based...

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Detalles Bibliográficos
Autores principales: Ewert, Donald, Hu, Ning, Du, Xiaoping, Li, Wei, West, Matthew B., Choi, Chul-Hee, Floyd, Robert, Kopke, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568441/
https://www.ncbi.nlm.nih.gov/pubmed/28832600
http://dx.doi.org/10.1371/journal.pone.0183089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568441/
https://www.ncbi.nlm.nih.gov/pubmed/28832600
http://dx.doi.org/10.1371/journal.pone.0183089

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