Skewing of the population balance of lymphoid and myeloid cells by secreted and intracellular osteopontin

The balance between myeloid and lymphoid populations must be well controlled. Here, we report that a protein, osteopontin (OPN), skews the balance between myeloid and lymphoid populations during pathogenic conditions, such as infection and autoimmunity. Importantly, two OPN isoforms exert distinct e...

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Detalles Bibliográficos
Autores principales: Kanayama, Masashi, Xu, Shengjie, Danzaki, Keiko, Gibson, Jason R., Inoue, Makoto, Gregory, Simon G., Shinohara, Mari L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568448/
https://www.ncbi.nlm.nih.gov/pubmed/28671690
http://dx.doi.org/10.1038/ni.3791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568448/
https://www.ncbi.nlm.nih.gov/pubmed/28671690
http://dx.doi.org/10.1038/ni.3791

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