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Skewing of the population balance of lymphoid and myeloid cells by secreted and intracellular osteopontin
The balance between myeloid and lymphoid populations must be well controlled. Here, we report that a protein, osteopontin (OPN), skews the balance between myeloid and lymphoid populations during pathogenic conditions, such as infection and autoimmunity. Importantly, two OPN isoforms exert distinct e...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568448/ https://www.ncbi.nlm.nih.gov/pubmed/28671690 http://dx.doi.org/10.1038/ni.3791 |