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Caenorhabditis elegans ATPase inhibitor factor 1 (IF(1)) MAI-2 preserves the mitochondrial membrane potential (Δψ(m)) and is important to induce germ cell apoptosis

When the electrochemical proton gradient is disrupted in the mitochondria, IF(1) (Inhibitor Factor-1) inhibits the reverse hydrolytic activity of the F(1)F(o)-ATP synthase, thereby allowing cells to conserve ATP at the expense of losing the mitochondrial membrane potential (Δψ(m)). The function of I...

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Detalles Bibliográficos
Autores principales: Fernández-Cárdenas, L. P., Villanueva-Chimal, E., Salinas, L. S., José-Nuñez, C., Tuena de Gómez Puyou, M., Navarro, R. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568743/
https://www.ncbi.nlm.nih.gov/pubmed/28829773
http://dx.doi.org/10.1371/journal.pone.0181984