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Caenorhabditis elegans ATPase inhibitor factor 1 (IF(1)) MAI-2 preserves the mitochondrial membrane potential (Δψ(m)) and is important to induce germ cell apoptosis
When the electrochemical proton gradient is disrupted in the mitochondria, IF(1) (Inhibitor Factor-1) inhibits the reverse hydrolytic activity of the F(1)F(o)-ATP synthase, thereby allowing cells to conserve ATP at the expense of losing the mitochondrial membrane potential (Δψ(m)). The function of I...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568743/ https://www.ncbi.nlm.nih.gov/pubmed/28829773 http://dx.doi.org/10.1371/journal.pone.0181984 |