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Exogenous growth factors bFGF, EGF and HGF do not influence viability and phenotype of (V600E)BRAF melanoma cells and their response to vemurafenib and trametinib in vitro

It has been shown that the response of (V600E)BRAF melanoma cells to targeted therapeutics is affected by growth factors. We have investigated the influence of three different growth factors, bFGF, EGF and HGF used either alone or in combination, on the response of (V600E)BRAF melanoma cell populati...

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Detalles Bibliográficos
Autores principales: Zalesna, Izabela, Osrodek, Marta, Hartman, Mariusz L., Rozanski, Michal, Sztiller-Sikorska, Malgorzata, Niewinna, Karolina, Nejc, Dariusz, Czyz, Malgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568748/
https://www.ncbi.nlm.nih.gov/pubmed/28829835
http://dx.doi.org/10.1371/journal.pone.0183498