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The ERK-1 function is required for HSV-1-mediated G1/S progression in HEP-2 cells and contributes to virus growth

The herpes simplex virus 1 is able to readdress different cellular pathways including cell cycle to facilitate its replication and spread. During infection, the progression of the cell cycle from G1 to S phase makes the cellular replication machinery accessible to viral DNA replication. In this work...

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Detalles Bibliográficos
Autores principales: Colao, Ivana, Pennisi, Rosamaria, Venuti, Assunta, Nygårdas, Michaela, Heikkilä, Outi, Hukkanen, Veijo, Sciortino, Maria Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569015/
https://www.ncbi.nlm.nih.gov/pubmed/28835716
http://dx.doi.org/10.1038/s41598-017-09529-y