Development of a novel immunoassay to detect interactions with the transactivation domain of p53: application to screening of new drugs

Tumor protein p53 acts as a trans-activator that negatively regulates cell division by controlling a set of genes required for cell cycle regulation, making it a tumor suppressor in different types of tumors. Because the transcriptional activity of p53 plays an important role in the occurrence and d...

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Detalles Bibliográficos
Autores principales: Xiong, Yufeng, Wu, Yingsong, Luo, Shuhong, Gao, Yang, Xiong, Yujing, Chen, Daxiang, Deng, Hao, Hao, Wenbo, Liu, Tiancai, Li, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569017/
https://www.ncbi.nlm.nih.gov/pubmed/28835687
http://dx.doi.org/10.1038/s41598-017-09574-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569017/
https://www.ncbi.nlm.nih.gov/pubmed/28835687
http://dx.doi.org/10.1038/s41598-017-09574-7

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