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Modulation of SOX2 expression delineates an end-point for paclitaxel-effectiveness in breast cancer stem cells
Tumor relapse in triple negative breast cancer patients has been implicated to chemoresistant cancer stem cells (CSCs), which under favorable conditions culminate in tumor re-formation and metastasis. Hence, eradication of CSCs during systemic chemotherapy is imperative. CSCs were sorted using immun...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569040/ https://www.ncbi.nlm.nih.gov/pubmed/28835684 http://dx.doi.org/10.1038/s41598-017-08971-2 |