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Modulation of SOX2 expression delineates an end-point for paclitaxel-effectiveness in breast cancer stem cells

Tumor relapse in triple negative breast cancer patients has been implicated to chemoresistant cancer stem cells (CSCs), which under favorable conditions culminate in tumor re-formation and metastasis. Hence, eradication of CSCs during systemic chemotherapy is imperative. CSCs were sorted using immun...

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Detalles Bibliográficos
Autores principales: Mukherjee, Pritha, Gupta, Arnab, Chattopadhyay, Dhrubajyoti, Chatterji, Urmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569040/
https://www.ncbi.nlm.nih.gov/pubmed/28835684
http://dx.doi.org/10.1038/s41598-017-08971-2