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RIPK1 protects hepatocytes from death in Fas-induced hepatitis

Hepatocyte death is a central event during liver disease progression, in which immune cells play key roles by activating members of the Tumor Necrosis Factor Receptor Superfamily (TNFRSF), including TNFR1 (TNFRSF1A), Fas (TNFRSF6) and TRAIL-R2 (TNFRSF10B). Receptor Interacting Protein Kinase 1 (RIPK...

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Detalles Bibliográficos
Autores principales: Filliol, Aveline, Farooq, Muhammad, Piquet-Pellorce, Claire, Genet, Valentine, Dimanche-Boitrel, Marie-Thérèse, Vandenabeele, Peter, Bertrand, Mathieu J. M., Samson, Michel, Le Seyec, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569041/
https://www.ncbi.nlm.nih.gov/pubmed/28835677
http://dx.doi.org/10.1038/s41598-017-09789-8