Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation

Activation of autophagy and elevation of glutamine synthesis represent key adaptations to maintain amino acid balance during starvation. In this study, we investigate the role of autophagy and glutamine on the regulation of mTORC1, a critical kinase that regulates cell growth and proliferation. We r...

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Detalles Bibliográficos
Autores principales: Tan, Hayden Weng Siong, Sim, Arthur Yi Loong, Long, Yun Chau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569045/
https://www.ncbi.nlm.nih.gov/pubmed/28835610
http://dx.doi.org/10.1038/s41467-017-00369-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569045/
https://www.ncbi.nlm.nih.gov/pubmed/28835610
http://dx.doi.org/10.1038/s41467-017-00369-y

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