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Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation
Activation of autophagy and elevation of glutamine synthesis represent key adaptations to maintain amino acid balance during starvation. In this study, we investigate the role of autophagy and glutamine on the regulation of mTORC1, a critical kinase that regulates cell growth and proliferation. We r...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569045/ https://www.ncbi.nlm.nih.gov/pubmed/28835610 http://dx.doi.org/10.1038/s41467-017-00369-y |