Cutaneous pigmentation modulates skin sensitivity via tyrosinase-dependent dopaminergic signalling

We propose a new mechanism of sensory modulation through cutaneous dopaminergic signalling. We hypothesize that dopaminergic signalling contributes to differential cutaneous sensitivity in darker versus lighter pigmented humans and mouse strains. We show that thermal and mechanical cutaneous sensiti...

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Detalles Bibliográficos
Autores principales: Ono, Kentaro, Viet, Chi T., Ye, Yi, Dang, Dongmin, Hitomi, Suzuro, Toyono, Takashi, Inenaga, Kiyotoshi, Dolan, John C., Schmidt, Brian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569050/
https://www.ncbi.nlm.nih.gov/pubmed/28835637
http://dx.doi.org/10.1038/s41598-017-09682-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569050/
https://www.ncbi.nlm.nih.gov/pubmed/28835637
http://dx.doi.org/10.1038/s41598-017-09682-4

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