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Neuroprotective Effects of CGP3466B on Apoptosis Are Modulated by Protein-L-isoaspartate (D-aspartate) O-methyltransferase/Mst1 Pathways after Traumatic Brain Injury in Rats

Neuronal apoptosis chiefly contributes to the cell loss following traumatic brain injury (TBI). CGP3466B is a compound related to the anti-Parkinsonism drug R-(−)-deprenyl. Previous studies have illuminated anti-apoptosis effects of CGP3466B in different cell lines, but the underlying mechanisms hav...

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Detalles Bibliográficos
Autores principales: Liang, Feng, Shi, Ligen, Zheng, Jingwei, Chen, Sheng, Wang, Yangxin, Zhang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569064/
https://www.ncbi.nlm.nih.gov/pubmed/28835703
http://dx.doi.org/10.1038/s41598-017-08196-3