Hypoxia imaging in cells and tumor tissues using a highly selective fluorescent nitroreductase probe

Hypoxia is a characteristic of locally advanced solid tumors, resulting from an imbalance between oxygen consumption and supply. In hypoxic solid tumors, an increased expression of nitroreductase (NTR) is detected, therefore, the development of NTR-targeted fluorescent probes to selectively and effi...

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Detalles Bibliográficos
Autores principales: Yang, Dan, Tian, Hang Yu, Zang, Tie Nan, Li, Ming, Zhou, Ying, Zhang, Jun Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569069/
https://www.ncbi.nlm.nih.gov/pubmed/28835695
http://dx.doi.org/10.1038/s41598-017-09525-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569069/
https://www.ncbi.nlm.nih.gov/pubmed/28835695
http://dx.doi.org/10.1038/s41598-017-09525-2

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