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Hypoxia imaging in cells and tumor tissues using a highly selective fluorescent nitroreductase probe
Hypoxia is a characteristic of locally advanced solid tumors, resulting from an imbalance between oxygen consumption and supply. In hypoxic solid tumors, an increased expression of nitroreductase (NTR) is detected, therefore, the development of NTR-targeted fluorescent probes to selectively and effi...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569069/ https://www.ncbi.nlm.nih.gov/pubmed/28835695 http://dx.doi.org/10.1038/s41598-017-09525-2 |