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Dietary Fat Intake Modulates Effects of a Frequent ACE Gene Variant on Glucose Tolerance with association to Type 2 Diabetes

The frequent ACE insertion/deletion polymorphism (I/D) is, albeit inconsistently, associated with impaired glucose tolerance and insulin resistance. We recently observed an enhanced upregulation of ACE by elevated fat intake in GG-carriers of the I/D-surrogate rs4343 variant and therefore investigat...

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Detalles Bibliográficos
Autores principales: Schüler, Rita, Osterhoff, Martin A., Frahnow, Turid, Möhlig, Matthias, Spranger, Joachim, Stefanovski, Darko, Bergman, Richard N., Xu, Li, Seltmann, Anne-Cathrin, Kabisch, Stefan, Hornemann, Silke, Kruse, Michael, Pfeiffer, Andreas F. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569105/
https://www.ncbi.nlm.nih.gov/pubmed/28835639
http://dx.doi.org/10.1038/s41598-017-08300-7