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Phenotyping first-generation genome editing mutants: a new standard?

The unprecedented efficiency of the CRISPR/Cas9 system in genome engineering has opened the prospect of employing mutant founders for phenotyping cohorts, thus accelerating research projects by circumventing the requirement to generate cohorts using conventional two- or three-generation crosses. How...

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Detalles Bibliográficos
Autores principales: Teboul, Lydia, Murray, Stephen A., Nolan, Patrick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569115/
https://www.ncbi.nlm.nih.gov/pubmed/28756587
http://dx.doi.org/10.1007/s00335-017-9711-x