Cargando…
Phenotyping first-generation genome editing mutants: a new standard?
The unprecedented efficiency of the CRISPR/Cas9 system in genome engineering has opened the prospect of employing mutant founders for phenotyping cohorts, thus accelerating research projects by circumventing the requirement to generate cohorts using conventional two- or three-generation crosses. How...
Autores principales: | Teboul, Lydia, Murray, Stephen A., Nolan, Patrick M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569115/ https://www.ncbi.nlm.nih.gov/pubmed/28756587 http://dx.doi.org/10.1007/s00335-017-9711-x |
Ejemplares similares
-
Application of long single-stranded DNA donors in genome editing: generation and validation of mouse mutants
por: Codner, Gemma F., et al.
Publicado: (2018) -
Screening and validation of genome-edited animals
por: Bunton-Stasyshyn, Rosie K, et al.
Publicado: (2021) -
Generation of mutant pigs by lipofection-mediated genome editing in embryos
por: Hirata, Maki, et al.
Publicado: (2021) -
Variability in Genome Editing Outcomes: Challenges for Research Reproducibility and Clinical Safety
por: Teboul, Lydia, et al.
Publicado: (2020) -
Phenotypic Characterization of High Carotenoid Tomato Mutants Generated by the Target-AID Base-Editing Technology
por: Hunziker, Johan, et al.
Publicado: (2022)