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Modeling human disease in rodents by CRISPR/Cas9 genome editing

Modeling human disease has proven to be a challenge for the scientific community. For years, generating an animal model was complicated and restricted to very few species. With the rise of CRISPR/Cas9, it is now possible to generate more or less any animal model. In this review, we will show how thi...

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Detalles Bibliográficos
Autores principales: Birling, Marie-Christine, Herault, Yann, Pavlovic, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569124/
https://www.ncbi.nlm.nih.gov/pubmed/28677007
http://dx.doi.org/10.1007/s00335-017-9703-x