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Editing the genome of hiPSC with CRISPR/Cas9: disease models
The advent of human-induced pluripotent stem cell (hiPSC) technology has provided a unique opportunity to establish cellular models of disease from individual patients, and to study the effects of the underlying genetic aberrations upon multiple different cell types, many of which would not normally...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer US
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569153/ https://www.ncbi.nlm.nih.gov/pubmed/28303292 http://dx.doi.org/10.1007/s00335-017-9684-9 |