Cytoplasmic domain of tissue factor promotes liver fibrosis in mice

AIM: To evaluate the role of tissue factor (TF) and protease activated receptor (PAR)-2 in liver fibrosis. METHODS: Using CCl(4) administration for eight weeks, we induced hepatic fibrosis in wild-type C57BL/6 mice and in mice with deletion of the cytoplasmic signalling domain of TF (TF(§CT/§CT)), d...

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Detalles Bibliográficos
Autores principales: Knight, Virginia, Lourensz, Dinushka, Tchongue, Jorge, Correia, Jeanne, Tipping, Peter, Sievert, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569283/
https://www.ncbi.nlm.nih.gov/pubmed/28883694
http://dx.doi.org/10.3748/wjg.v23.i31.5692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569283/
https://www.ncbi.nlm.nih.gov/pubmed/28883694
http://dx.doi.org/10.3748/wjg.v23.i31.5692

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