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Single-cell topological RNA-Seq analysis reveals insights into cellular differentiation and development

Transcriptional programs control cellular lineage commitment and differentiation during development. Understanding cell fate has been advanced by studying single-cell RNA-seq, but is limited by the assumptions of current analytic methods regarding the structure of data. We present single-cell topolo...

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Detalles Bibliográficos
Autores principales: Rizvi, Abbas H., Camara, Pablo G., Kandror, Elena K., Roberts, Thomas J., Schieren, Ira, Maniatis, Tom, Rabadan, Raul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569300/
https://www.ncbi.nlm.nih.gov/pubmed/28459448
http://dx.doi.org/10.1038/nbt.3854