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CCN5/WISP-2 restores ER-∝ in normal and neoplastic breast cells and sensitizes triple negative breast cancer cells to tamoxifen

CCN5/WISP-2 is an anti-invasive molecule and prevents breast cancer (BC) progression. However, it is not well understood how CCN5 prevents invasive phenotypes of BC cells. CCN5 protein expression is detected in estrogen receptor-α (ER-α) -positive normal breast epithelial cells as well as BC cells,...

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Detalles Bibliográficos
Autores principales: Sarkar, S, Ghosh, A, Banerjee, S, Maity, G, Das, A, Larson, M A, Gupta, V, Haque, I, Tawfik, O, Banerjee, S K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569333/
https://www.ncbi.nlm.nih.gov/pubmed/28530705
http://dx.doi.org/10.1038/oncsis.2017.43