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Glucuronides of phytoestrogen flavonoid enhance macrophage function via conversion to aglycones by β‐glucuronidase in macrophages

INTRODUCTION: Flavonoids are converted to inactive metabolites like glucuronides in the gut, and circulate mainly as glucuronides in blood stream, resulting in low concentrations of active aglycones in plasma. It is therefore unclear how oral flavonoids exert their effects in tissues. We recently re...

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Detalles Bibliográficos
Autores principales: Kaneko, Atsushi, Matsumoto, Takashi, Matsubara, Yosuke, Sekiguchi, Kyoji, Koseki, Junichi, Yakabe, Ryo, Aoki, Katsuyuki, Aiba, Setsuya, Yamasaki, Kenshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569364/
https://www.ncbi.nlm.nih.gov/pubmed/28480538
http://dx.doi.org/10.1002/iid3.163