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Broad Th2 neutralization and anti‐inflammatory action of pentosan polysulfate sodium in experimental allergic rhinitis

BACKGROUND: Th2 cytokines like interleukin‐4, ‐5, and ‐13 are regarded as important drivers of the immunopathology underlying allergic rhinitis (AR) and asthma. The present study explores the capacity of pentosan polysulfate sodium (PPS), a semi‐synthetic heparin‐like macromolecular carbohydrate, to...

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Detalles Bibliográficos
Autores principales: Sanden, Caroline, Mori, Michiko, Jogdand, Prajakta, Jönsson, Jimmie, Krishnan, Ravi, Wang, Xiangdong, Erjefält, Jonas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569365/
https://www.ncbi.nlm.nih.gov/pubmed/28497614
http://dx.doi.org/10.1002/iid3.164