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uPA‐derived peptide, Å6 is involved in the suppression of lipopolysaccaride‐promoted inflammatory osteoclastogenesis and the resultant bone loss

INTRODUCTION: Chronic inflammatory diseases such as rheumatoid arthritis and periodontitis frequently cause bone destruction. Inflammation‐induced bone loss results from the increase of bone‐resorbing osteoclasts. Recently, we demonstrated that urokinase type plasminogen activator (uPA) suppressed l...

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Detalles Bibliográficos
Autores principales: Kanno, Yosuke, Maruyama, Chihiro, Matsuda, Ayaka, Ishisaki, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569370/
https://www.ncbi.nlm.nih.gov/pubmed/28493442
http://dx.doi.org/10.1002/iid3.169