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Intestinal epithelial suppressor of cytokine signaling 3 (SOCS3) impacts on mucosal homeostasis in a model of chronic inflammation

INTRODUCTION: Suppressor of cytokine signaling 3 (SOCS3) is a tumour suppressor, limiting intestinal epithelial cell (IEC) proliferation in acute inflammation, and tumour growth, but little is known regarding its role in mucosal homeostasis. Resistance to the intestinal helminth Trichuris muris reli...

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Detalles Bibliográficos
Autores principales: Shaw, Elisabeth J., Smith, Emily E., Whittingham‐Dowd, Jayde, Hodges, Matthew D., Else, Kathryn J., Rigby, Rachael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569373/
https://www.ncbi.nlm.nih.gov/pubmed/28508554
http://dx.doi.org/10.1002/iid3.171