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Increased adipose tissue expression of IL‐18R and its ligand IL‐18 associates with inflammation and insulin resistance in obesity

INTRODUCTION: The proinflammatory cytokine IL‐18 is involved in the pathogenesis of metabolic syndrome. While the changes in IL‐18 are known, IL‐18R expression and relationship with IL‐18 and other inflammatory markers in the adipose tissue in obesity/type‐2 diabetes (T2D) remain unclear. METHODS: W...

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Detalles Bibliográficos
Autores principales: Ahmad, Rasheed, Thomas, Reeby, Kochumon, Shihab, Sindhu, Sardar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569378/
https://www.ncbi.nlm.nih.gov/pubmed/28508444
http://dx.doi.org/10.1002/iid3.170