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Coumarin derivatives bearing benzoheterocycle moiety: synthesis, cholinesterase inhibitory, and docking simulation study

OBJECTIVE(S): To investigate the efficiency of a novel series of coumarin derivatives bearing benzoheterocycle moiety as novel cholinesterase inhibitors. MATERIALS AND METHODS: Different 7-hydroxycoumarin derivatives were synthesized via Pechmann or Knoevenagel condensation and conjugated to differe...

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Detalles Bibliográficos
Autores principales: Hirbod, Kimia, Jalili-baleh, Leili, Nadri, Hamid, ebrahimi, Seyed esmaeil Sadat, Moradi, Alireza, Pakseresht, Bahar, Foroumadi, Alireza, Shafiee, Abbas, Khoobi, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569448/
https://www.ncbi.nlm.nih.gov/pubmed/28868119
http://dx.doi.org/10.22038/IJBMS.2017.8830