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Anti-inflammatory and immunomodulatory mechanisms of atorvastatin in a murine model of traumatic brain injury

BACKGROUND: Neuroinflammation is an important secondary injury mechanism that has dual beneficial and detrimental roles in the pathophysiology of traumatic brain injury (TBI). Compelling data indicate that statins, a group of lipid-lowering drugs, also have extensive immunomodulatory and anti-inflam...

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Detalles Bibliográficos
Autores principales: Xu, Xin, Gao, Weiwei, Cheng, Shiqi, Yin, Dongpei, Li, Fei, Wu, Yingang, Sun, Dongdong, Zhou, Shuai, Wang, Dong, Zhang, Yongqiang, Jiang, Rongcai, Zhang, Jianning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569493/
https://www.ncbi.nlm.nih.gov/pubmed/28835272
http://dx.doi.org/10.1186/s12974-017-0934-2