Plasmodium falciparum malaria parasite var gene expression is modified by host antibodies: longitudinal evidence from controlled infections of Kenyan adults with varying natural exposure

BACKGROUND: The PfEMP1 family of Plasmodium falciparum antigens play a key role in pathogenesis of severe malaria through their insertion into the surface of parasite infected erythrocytes, and adhesion to host cells. Previous studies have suggested that parasites expressing PfEMP1 subclasses group...

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Detalles Bibliográficos
Autores principales: Abdi, Abdirahman I., Hodgson, Susanne H., Muthui, Michelle K., Kivisi, Cheryl A., Kamuyu, Gathoni, Kimani, Domtila, Hoffman, Stephen L., Juma, Elizabeth, Ogutu, Bernhards, Draper, Simon J., Osier, Faith, Bejon, Philip, Marsh, Kevin, Bull, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569527/
https://www.ncbi.nlm.nih.gov/pubmed/28835215
http://dx.doi.org/10.1186/s12879-017-2686-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569527/
https://www.ncbi.nlm.nih.gov/pubmed/28835215
http://dx.doi.org/10.1186/s12879-017-2686-0

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