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A novel treatment approach for retinoblastoma by targeting epithelial growth factor receptor expression with a shRNA lentiviral system

OBJECTIVE(S): Non-invasive treatment options for retinoblastoma (RB), the most common malignant eye tumor among children, are lacking. Epithelial growth factor receptor (EGFR) accelerates cell proliferation, survival, and invasion of many tumors including RB. However, RB treatment by targeting EGFR...

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Detalles Bibliográficos
Autores principales: Chai, Yong, Xiao, Juhua, Du, Yunyan, Luo, Zhipeng, Lei, Jun, Zhang, Shouhua, Huang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569589/
https://www.ncbi.nlm.nih.gov/pubmed/28852437
http://dx.doi.org/10.22038/IJBMS.2017.9003