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Potential role of DNA methylation as a facilitator of target search processes for transcription factors through interplay with methyl-CpG-binding proteins

Eukaryotic genomes contain numerous non-functional high-affinity sequences for transcription factors. These sequences potentially serve as natural decoys that sequester transcription factors. We have previously shown that the presence of sequences similar to the target sequence could substantially i...

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Detalles Bibliográficos
Autores principales: Kemme, Catherine A., Marquez, Rolando, Luu, Ross H., Iwahara, Junji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569922/
https://www.ncbi.nlm.nih.gov/pubmed/28486614
http://dx.doi.org/10.1093/nar/gkx387