Cargando…

Pleiotropic Effects of Biguanides on Mitochondrial Reactive Oxygen Species Production

Metformin is widely prescribed as a first-choice antihyperglycemic drug for treatment of type 2 diabetes mellitus, and recent epidemiological studies showed its utility also in cancer therapy. Although it is in use since the 1970s, its molecular target, either for antihyperglycemic or antineoplastic...

Descripción completa

Detalles Bibliográficos
Autores principales: Pecinova, Alena, Drahota, Zdenek, Kovalcikova, Jana, Kovarova, Nikola, Pecina, Petr, Alan, Lukas, Zima, Michal, Houstek, Josef, Mracek, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569935/
https://www.ncbi.nlm.nih.gov/pubmed/28874953
http://dx.doi.org/10.1155/2017/7038603